drugset / Trial / NCT02339584

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

NCT02339584

Phase 3 Completed 493 enrolled Alcon Research
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to compare the fixed combination (BID) \[Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL eyes drops, suspension\] to the unfixed combination (BID) \[Brinzolamide 10 mg/mL eye drops, suspension plus Brimonidine 2 mg/mL eyes drops, solution\] with respect to intraocular pressure (IOP)-lowering efficacy.

Timeline

Start
2015-04-14
Primary completion
2016-11-01
Completion
2016-11-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Brimonidine Small molecule 2 mg/ml Topical
Comparator Brinzolamide Small molecule 10 mg/ml Topical