A Pilot Clinical Trial of Oral Ketamine for Acute Pain Management After Amputation Surgery

NCT02341963 ↗

Phase 1 Terminated 5 enrolled Rush University Medical Center

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this pilot study is to test the safety of oral ketamine to treat acute pain after amputation surgery. The objective of the proposed research is to conclusively determine if oral ketamine is a safe alternative analgesic to opioid for acute pain in subjects undergoing elective amputation of the lower extremity. All participants will receive oral ketamine.

Timeline

Start: 2015-01
Primary completion: 2020-12
Completion: 2021-01

Publications

Results Buvanendran A, Kroin JS, Rajagopal A, Robison SJ, Moric M, Tuman KJ. Oral Ketamine for Acute Pain Management After Amputation Surgery. Pain Med. 2018 Jun 1;19(6):1265-1270. doi: 10.1093/pm/pnx229.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ketamine	Small molecule	1 mg/kg	Oral

Indications

No indication recorded.