drugset / Trial / NCT02343718

Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CNS Tumours

NCT02343718

Phase 1 Completed 7 enrolled Canadian Cancer Trials Group Pfizer · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the best dose of vinblastine that can be given with a new drug, temsirolimus.

Timeline

Start
2015-06-24
Primary completion
2017-09-28
Completion
2019-01-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Temsirolimus Small molecule 0.5 mg/kg Intravenous
Subject Temsirolimus Small molecule 10 mg/m2 Intravenous
Subject Temsirolimus Small molecule 15 mg/m2 Intravenous
Subject Vinblastine Small molecule 0.13 mg/kg Intravenous
Subject Vinblastine Small molecule 4 mg/m2 Intravenous