drugset / Trial / NCT02350868
Dose-Seeking Study of MPT0E028 in Subjects With Advanced Solid Malignancies Without Standard Treatment
NaSingle-groupOpen-labelTreatment
Summary
The Dose Escalation Phase will determine the MTD of MPT0E028 and evaluate its safety and tolerability, PK, PD, and preliminary clinical effects; the subsequent Dose Confirmation Phase will be a cohort expansion at or below the MTD (i.e., an RP2D) of MPT0E028.
Timeline
- Start
- 2015-04-24
- Primary completion
- 2019-01-19
- Completion
- 2019-01-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ABT-301 | Unknown | 50 mg | Oral |