drugset / Trial / NCT02350868

Dose-Seeking Study of MPT0E028 in Subjects With Advanced Solid Malignancies Without Standard Treatment

NCT02350868

Phase 1 Completed 23 enrolled Taipei Medical University
NaSingle-groupOpen-labelTreatment

Summary

The Dose Escalation Phase will determine the MTD of MPT0E028 and evaluate its safety and tolerability, PK, PD, and preliminary clinical effects; the subsequent Dose Confirmation Phase will be a cohort expansion at or below the MTD (i.e., an RP2D) of MPT0E028.

Timeline

Start
2015-04-24
Primary completion
2019-01-19
Completion
2019-01-19

Drugs

EvaluationDrugModalityDoseRoute
Subject ABT-301 Unknown 50 mg Oral