Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney

Summary

Renal Insufficiency is a priority disease in health system, which may require renal replacement therapy based on renal transplantation, which is considered as therapy of choice. During the procedure of renal transplantation, the graft could be damaged by ischemia-reperfusion which generates complications in its function. Recently the anti-inflammatory and immunomodulatory effects of statins have been emphasized, which could be beneficial in renal transplantation.

Timeline

Start

2012-01

Primary completion

2014-04

Completion

2014-07

Drugs

Indications