drugset / Trial / NCT02360202
Evaluation of Fluid Retention Due to Superpotent Topical Corticosteroid
NaSingle-groupPrevention
Summary
Clinical observation frequently shows a paradoxical effect of topical corticosteroids in charge of a sudden melting of edema in the first days of treatment, which could be due to mobilization of extracellular. No study has shown the value of this measure in patients treated with topical steroids. This uncertainty, coupled with the observation of the paradoxical effects of topical steroids on edema are some patients that despite the systemic absorption of clobetasol propionate, a salt-free diet is not currently recommended practice.
Timeline
- Start
- 2015-02-17
- Primary completion
- 2017-02-28
- Completion
- 2017-02-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | clobetasol propionate | Small molecule | 10 g | Topical |
| Subject | clobetasol propionate | Small molecule | 40 g | Topical |