Biomarkers of Neuroinflammation and Anti-Inflammatory Treatments in Major Depressive Disorder

Summary

The purpose of this study is to determine if translocator protein total distribution volume (TSPO VT) is elevated in major depressive disorder that is not responding to medication and if adding minocycline can affect TSPO VT. Many remain treatment resistant with common antidepressant treatments and the investigators think it may be due to poor targeting of brain pathologies.

Timeline

Start

2015-02

Primary completion

2019-04

Completion

2019-04

Drugs

Indications