Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response

Summary

Background: Colchicine is an old well-known venerable drug routinely used in gout attacks for instance. More recnetly it is regularly use in the treatment of pericarditis. It couls exert antiiflammatory effects targeting the adverse inflammation occuring incase of acute myocardial infarction, which is involved in poor outcomes or longer stay at hospital. Endpoints: * Main endpoint: AUC CRP during the initial hospital stay * Secondary endpoints: * Clinical: oucomes * Imaging: ETT, MRI * Biological: various biomarkers Method Randomized, controled, open-labbelled, comparing two parallel arms: conventionnal optimal treatment versus conventionnal optimal treatment + colchicine

Timeline

Start

2014-12

Primary completion

2016-05

Completion

2016-08

Drugs

Indications