drugset / Trial / NCT02367170
Project 4A: Inspiratory Muscle Training and Diaphragm Strength
Phase 1/2
Terminated
1 enrolled
University of Florida
National Institute of General Medical Sciences (NIGMS) · collab
RandomizedParallel-groupSingle-blindPrevention
Summary
Investigators will assess the effect of exercise on markers of inflammation and protein catabolism. This research study will further our understanding of how treating Chronic Critical illness (CCI) - related respiratory muscle weakness with strength training can not only improve muscle function, but also potentially blunt the inflammation and catabolism of Peristent Inflammation/Immunosuppression and Catabolism (PICS).
Timeline
- Start
- 2015-03
- Primary completion
- 2015-07
- Completion
- 2015-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Midazolam | Small molecule | 0.5 mg | Intravenous |
| Background | Midazolam | Small molecule | 2 mg | Intravenous |