Esmolol to Treat the Hemodynamic Effects of Septic Shock

Phase 2 Terminated 40 enrolled Beth Israel Deaconess Medical Center American Heart Association · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The main purpose of this study is to determine the effects of controlling the heart rate of patients with septic shock using an intravenous medication called esmolol.

Timeline

Start: 2015-03
Primary completion: 2019-12-31
Completion: 2019-12-31

Outcome

Outcome not reported

Stopped (Enrollment): “Funding expired, low enrollments”

Publications

Cocchi MN, Dargin J, Chase M, Patel PV, Grossestreuer A, Balaji L, Liu X, Moskowitz A, Berg K, Donnino MW. Esmolol to Treat the Hemodynamic Effects of Septic Shock: A Randomized Controlled Trial. Shock. 2022 Apr 1;57(4):508-517. doi: 10.1097/SHK.0000000000001905.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Esmolol	Other / unclassified	—	Intravenous