Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy

Phase 3 Unknown 118 enrolled University of Erlangen-Nürnberg Medical School

RandomizedParallel-groupOpen-labelTreatment

Summary

Randomized study to investigate the efficacy of deep regional hyperthermia in patients with anal carcinoma treated by standard radiochemotherapy with MMC and 5-FU.

Timeline

Start: 2014-12
Primary completion: 2017-12
Completion: 2021-04

Publications

Ott OJ, Schmidt M, Semrau S, Strnad V, Matzel KE, Schneider I, Raptis D, Uter W, Grutzmann R, Fietkau R. Chemoradiotherapy with and without deep regional hyperthermia for squamous cell carcinoma of the anus. Strahlenther Onkol. 2019 Jul;195(7):607-614. doi: 10.1007/s00066-018-1396-x. Epub 2018 Nov 2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	Mitomycin C	Other / unclassified	10 mg/m2	—
Background	fluorouracil	Small molecule	1000 mg/m2	—

Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy

Summary

Timeline

Publications

Drugs

Indications