HM2014-26 DT2219 for Relapsed or Refractory B-Lineage Leukemia or Lymphoma

Summary

This is a phase I/II study of DT2219 for the treatment of relapsed or refractory CD19 (+) and/or CD 22 (+) B-lineage leukemia and lymphoma. The study consists of two phases - a phase I dose/schedule finding component using the maximum tolerated dose identified during the previous phase I study, but with a higher number of doses and a two-stage phase II extension component to confirm safety and make a preliminary determination of the activity level by disease using the dose identified in phase I.

Timeline

Start

2015-12-21

Primary completion

2018-04-08

Completion

2018-04-08

Drugs

Indications