Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis

Summary

This is a randomized, double-blind, placebo-controlled study of oral cromolyn sodium when made into a viscous preparation for the treatment of eosinophilic esophagitis.

Timeline

Start

2014-12

Primary completion

2017-07

Completion

2017-12

Outcome

Missed primary endpoint

paper Cromolyn, when mixed into a viscous preparation, did not significantly decrease esophageal eosinophilia. PMID 29544738 ↗

Publications

• Lieberman JA, Zhang J, Whitworth J, Cavender C. A randomized, double-blinded, placebo-controlled study of the use of viscous oral cromolyn sodium for the treatment of eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2018 May;120(5):527-531. doi: 10.1016/j.anai.2018.03.006. Epub 2018 Mar 12.

Drugs

Indications