Study of Radiotracer [18F]Fluortriopride ([18F]FTP) by PET/CT

Phase 1 Completed 29 enrolled University of Pennsylvania

Non-randomizedParallel-groupOpen-labelOther

Summary

In this phase 1 pilot study, positron emission tomography (PET/CT) imaging will be used to determine the biodistribution, metabolism and excretion of a novel radiotracer \[18F\]Fluortriopride (\[18F\]FTP).

Timeline

Start: 2015-03-27
Primary completion: 2026-06-09
Completion: 2026-06-09

Publications

Background Mach RH, Tu Z, Xu J, Li S, Jones LA, Taylor M, Luedtke RR, Derdeyn CP, Perlmutter JS, Mintun MA. Endogenous dopamine (DA) competes with the binding of a radiolabeled D(3) receptor partial agonist in vivo: a positron emission tomography study. Synapse. 2011 Aug;65(8):724-32. doi: 10.1002/syn.20891. Epub 2011 Mar 21.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	[18F]Fluortriopride	Diagnostic / imaging agent	—	—

Indications

No indication recorded.