Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease

Summary

Sialorrhea is a frequently occurring problem with detrimental effect on quality of life in 25% of PD patients. Currently, there is no intervention approved for sialorrhea in Parkinsons and evidence is only available for a 30-day effect or less. We hypothesize that glycopyrrolate will have a lasting effect in the reduction of sialorrhea in PD patients.

Timeline

Start

2016-07

Primary completion

2018-10

Completion

2018-12

Drugs

Indications