drugset / Trial / NCT02382640
Effect of Antacid on Bioavailability of Febuxostat After Administration of a Febuxostat 80 mg Extended-Release Capsule
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to assess the effect of antacid administration, and its timing, on the bioavailability of a single dose of febuxostat extended-release (XR) 80 mg.
Timeline
- Start
- 2015-03
- Primary completion
- 2015-05
- Completion
- 2015-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aluminum hydroxide | Unknown | 200 mg | Oral |
| Subject | Febuxostat | Small molecule | 80 mg | Oral |
| Subject | Simethicone | Other / unclassified | 20 mg | Oral |
| Subject | magnesium hydroxide | Unknown | 200 mg | Oral |
Indications
No indication recorded.