drugset / Trial / NCT02383043

Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer

NCT02383043

Phase 0 Completed 18 enrolled University of Kentucky
RandomizedCrossoverDouble-blindBasic science

Summary

Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate choice self-administration procedures between drug and a non-drug alternative reinforcer presented during maintenance on d-amphetamine, which has been previously shown to reduce cocaine use.

Timeline

Start
2015-02-01
Primary completion
2018-04-05
Completion
2018-04-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Cocaine Small molecule
Subject Dextroamphetamine Small molecule