drugset / Trial / NCT02383043
Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer
RandomizedCrossoverDouble-blindBasic science
Summary
Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate choice self-administration procedures between drug and a non-drug alternative reinforcer presented during maintenance on d-amphetamine, which has been previously shown to reduce cocaine use.
Timeline
- Start
- 2015-02-01
- Primary completion
- 2018-04-05
- Completion
- 2018-04-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cocaine | Small molecule | — | — |
| Subject | Dextroamphetamine | Small molecule | — | — |