drugset / Trial / NCT02384317

Open-Label Study to Evaluate Safety and Efficacy of CCX168 in Subjects With IGA Nephropathy on Stable RAAS Blockade

NCT02384317

Phase 2 Completed 7 enrolled Amgen
NaSingle-groupOpen-labelTreatment

Summary

The primary safety objective of this study is to evaluate the safety and tolerability of CCX168 in subjects with IgAN on background supportive therapy with a maximally tolerated dose of RAAS blockade. The primary efficacy objective is to evaluate the efficacy of CCX168 based on an improvement in proteinuria.

Timeline

Start
2015-03-27
Primary completion
2015-09-13
Completion
2018-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Avacopan Small molecule 30 mg Oral