Temozolomide and Concomitant Whole Brain Radiotherapy in NSCLC Patients With Brain Metastases

Summary

The purpose of this study is to evaluate the safety profile and efficacy of whole brain radiotherapy (WBRT) concomitantly with temozolomide (TMZ) in patients with brain metastases (BM).Patients with BM were randomly assigned to 30 Gy of WBRT with or without concomitant TMZ (75 mg/m2/d) plus two cycles of TMZ (200 mg/m2/d for 5 days).

Timeline

Start

2015-04

Primary completion

2016-12

Completion

2018-12

Drugs

Indications