drugset / Trial / NCT02385669

A Phase I/II Trial to Evaluate a Peptide Vaccine Plus Ipilimumab in Patients With Melanoma

NCT02385669

Phase 1/2 Terminated 3 enrolled Craig L Slingluff, Jr
NaSingle-groupOpen-labelTreatment

Summary

This study evaluates whether it is safe to administer a peptide vaccine with ipilimumab. This study will also evaluate the effects of the combination of the peptide vaccine and ipilimumab on the immune system. The investigators will monitor these effects by performing tests in the laboratory on participants' blood, a lymph node, and tumor samples.

Timeline

Start
2015-04
Primary completion
2019-09-18
Completion
2019-09-18

Drugs

EvaluationDrugModalityDoseRoute
Subject 6MHP Vaccine 200 ug Subcutaneous
Subject Ipilimumab Monoclonal antibody 3 mg/kg Intravenous

Indications