drugset / Trial / NCT02395692
Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma
NaSingle-groupOpen-labelTreatment
Summary
This phase II trial studies how well methoxyamine works when added to standard temozolomide in treating patients with glioblastoma that has come back. Drugs used in chemotherapy, such as methoxyamine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Timeline
- Start
- 2015-12-18
- Primary completion
- 2017-02-16
- Completion
- 2017-02-16
Outcome
Outcome not reported
Stopped: “Pre-specified response criteria not met to proceed to next stage of study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methoxyamine | Small molecule | — | Oral |
| Subject | Temozolomide | Small molecule | — | Oral |