drugset / Trial / NCT02405637

Simulated Amniotic Fluid In Preventing Feeding Intolerance and Necrotizing Enterocolitis VLBW Neonates

NCT02405637 ↗

Phase 1 Unknown 40 enrolled Rania Ali El-Farrash
RandomizedParallel-groupTriple-blindPrevention

Summary

The human fetus swallows over 200 ml of amniotic fluid per kilogram of weight each day and such swallowing is essential for normal small bowel development.Growth factors found in the amniotic fluid have been shown to promote proliferation of fetal intestinal cells. As feeding intolerance is a common problem among premature neonates, the investigators will study the role of enteral administration of simulated amniotic fluid solution in prevention of feeding intolerance and NEC in premature neonates.

Timeline

Start
2014-03
Primary completion
2015-03
Completion
2015-05

Drugs

EvaluationDrugModalityDoseRoute
Subject simulated amniotic fluid Unknown 20 unknown Other