Emergency Contraception and Body Weight: Pilot Study

Phase 4 Completed 10 enrolled Oregon Health and Science University Medical Research Foundation, Oregon · collab

Non-randomizedParallel-groupOpen-labelOther

Summary

The purpose of this research study is to determine how body weight changes the drug level of an emergency contraceptive pill containing a hormone called levonorgestrel (LNG). This emergency contraceptive is available to women without a prescription, but has recently been found to not work as well to prevent pregnancies in women of higher body weight. The overall goal of this research is to improve the effectiveness of contraception for women, no matter their weight.

Timeline

Start: 2015-02
Primary completion: 2015-07
Completion: 2015-08

Publications

Results Edelman AB, Cherala G, Blue SW, Erikson DW, Jensen JT. Impact of obesity on the pharmacokinetics of levonorgestrel-based emergency contraception: single and double dosing. Contraception. 2016 Jul;94(1):52-7. doi: 10.1016/j.contraception.2016.03.006. Epub 2016 Mar 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Levonorgestrel	Small molecule	1.5 mg	Oral
Subject	Levonorgestrel	Small molecule	3 mg	Oral

Indications

No indication recorded.