drugset / Trial / NCT02409433
Comparative Trial of IV Lacosamide Versus Phenytoin for Seizure Management
Phase 4
Terminated
3 enrolled
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
UCB Pharma · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The Investigator plans to perform a prospective, randomized, single blinded, study that will compare patients treated with IV lacosamide to those treated with Phenytoin in the Intensive Care Unit (ICU) setting. The investigator will also evaluate the rate of clinically evident and sub-clinical seizures, and to compare long-term outcomes between patients treated with lacosamide and those treated with Phenytoin.
Timeline
- Start
- 2014-08
- Primary completion
- 2015-11
- Completion
- 2015-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lacosamide | Other / unclassified | 400 mg | Intravenous |
| Comparator | Phenytoin | Unknown | 5 mg/kg | Intravenous |