drugset / Trial / NCT02410499

Efficacy and Safety of Weekly Subcutaneous MLN1202 in Improving Diabetic Nephropathy in Participants With Macroalbuminuria

NCT02410499

Phase 2 Withdrawn Takeda
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to characterize the effects of 85 days treatment with MLN1202 on urinary albumin-to-creatinine ratio (UACR) in participants with type 2 diabetes, advanced kidney disease/diabetic nephropathy (DN) and macro-albuminuria (UACR\>300 mg/g) based on average of 3 consecutive first morning voids sample collection.

Timeline

Start
2015-05-20
Primary completion
2015-11-17
Completion
2015-11-17

Drugs

EvaluationDrugModalityDoseRoute
Subject PLOZALIZUMAB Monoclonal antibody 75 mg Subcutaneous
Subject PLOZALIZUMAB Monoclonal antibody 105 mg Subcutaneous
Subject PLOZALIZUMAB Monoclonal antibody 150 mg Subcutaneous