drugset / Trial / NCT02410499
Efficacy and Safety of Weekly Subcutaneous MLN1202 in Improving Diabetic Nephropathy in Participants With Macroalbuminuria
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to characterize the effects of 85 days treatment with MLN1202 on urinary albumin-to-creatinine ratio (UACR) in participants with type 2 diabetes, advanced kidney disease/diabetic nephropathy (DN) and macro-albuminuria (UACR\>300 mg/g) based on average of 3 consecutive first morning voids sample collection.
Timeline
- Start
- 2015-05-20
- Primary completion
- 2015-11-17
- Completion
- 2015-11-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PLOZALIZUMAB | Monoclonal antibody | 75 mg | Subcutaneous |
| Subject | PLOZALIZUMAB | Monoclonal antibody | 105 mg | Subcutaneous |
| Subject | PLOZALIZUMAB | Monoclonal antibody | 150 mg | Subcutaneous |