drugset / Trial / NCT02410525
A Study Testing A Radioactive Compound Given Through A Vein With And Without The Non-Radioactive Compound, Given By Mouth, To Characterize Tissue Distribution Using Positron Emission Tomography Scanning
RandomizedCrossoverOpen-labelBasic science
Summary
In this study, radioactive PF-06427878 will be administered, through a vein, alone and with 2 different oral doses of non-radioactive PF-06427878 to healthy, adult, male subjects. Positron emission tomography will be used to characterize tissue distribution. The study will also characterize how the study drug behaves in the body, its safety, and how the body tolerates it.
Timeline
- Start
- 2015-05
- Primary completion
- 2015-09
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PF-06427878 | Small molecule | 20 ug | Intravenous |
| Subject | PF-06427878 | Small molecule | 10 mg | Intravenous |
| Subject | PF-06427878 | Small molecule | 600 mg | Intravenous |
Indications
No indication recorded.