Bendamustine Study in Classical Hodgkin Lymphoma Patients Over 60 Treated by Prednisone, Vinblastine and Doxorubicin

Phase 2 Completed 90 enrolled The Lymphoma Academic Research Organisation

NaSingle-groupOpen-labelTreatment

Summary

This study evaluates bendamustine in patients aged over 60 years with classical Hodgkin Lymphoma treated by prednisone, vinblastine and doxorubicin. 90 patients will be enrolled in this study.

Timeline

Start: 2015-07-17
Primary completion: 2018-12-14
Completion: 2020-11-10

Publications

Ghesquieres H, Krzisch D, Nicolas-Virelizier E, Kanoun S, Gac AC, Guidez S, Touati M, Laribi K, Morschhauser F, Bonnet C, Waultier-Rascalou A, Orsini-Piocelle F, Andre M, Fournier M, Morand F, Berriolo-Riedinger A, Burroni B, Damotte D, Traverse-Glehen A, Quittet P, Casasnovas O. The phase 2 LYSA study of prednisone, vinblastine, doxorubicin, and bendamustine for untreated Hodgkin lymphoma in older patients. Blood. 2024 Mar 14;143(11):983-995. doi: 10.1182/blood.2023021564.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bendamustine	Small molecule	120 mg/m2	Intravenous
Background	Doxorubicin	Other / unclassified	40 mg/m2	Intravenous
Background	Prednisone	Other / unclassified	40 mg/m2	Oral
Background	Vinblastine	Small molecule	6 mg/m2	Intravenous

Bendamustine Study in Classical Hodgkin Lymphoma Patients Over 60 Treated by Prednisone, Vinblastine and Doxorubicin

Summary

Timeline

Publications

Drugs

Indications