drugset / Trial / NCT02414607

Effect of Elderberry Juice on Cognition and Inflammation in Patients With Mild Cognitive Impairment

NCT02414607 ↗

Phase 1/2 Completed 24 enrolled University of Missouri-Columbia
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Elderberries (Sambuci fructus) have been shown in a number of studies to have significant anti-inflammatory and antioxidant effects. Multiple human and animal studies have supported the anti-inflammatory and antioxidant effects of elderberry preparations and it has been used in natural medicine for hundreds of years. Studies examining factors that may decrease the risk of Alzheimer's disease have revealed that drinking juices with similar properties to elderberries is one of the most reliable way to decrease risk. As such the investigators wish to determine the effects of elderberry juice on cognitive decline in a group of subjects at high risk for Alzheimer's disease, those with mild cognitive impairment. Elderberry juice is a commercially available nutritional supplement and easily available to this population.

Timeline

Start
2016-09
Primary completion
2019-12
Completion
2019-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Elderberry Juice Traditional medicine (herbal / TCM) 5 ml Oral