drugset / Trial / NCT02419508

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

NCT02419508

Phase 4 Completed 290 enrolled Alcon Research
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of brinzolamide 1%/brimonidine 0.2% (dosed twice per day (BID)) when added to a prostaglandin analogue (PGA) in subjects with open-angle glaucoma or ocular hypertension.

Timeline

Start
2015-08-07
Primary completion
2018-02-27
Completion
2018-02-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Brimonidine Small molecule 0.2 % Other
Subject Brinzolamide Small molecule 1 % Other
Background Bimatoprost Other / unclassified 0.01 % Other
Background Latanoprost Small molecule 0.005 % Other
Background Travoprost Other / unclassified 0.004 % Other