drugset / Trial / NCT02424916

Adoptive Transfer of Specific Melanoma Antigens CD8+ T Cells in Metastatic Melanoma Patients: a Phase I/II Study

NCT02424916 ↗

Phase 1/2 Completed 7 enrolled Nantes University Hospital UMR892 · collab
NaSingle-groupOpen-labelTreatment

Summary

This study evaluates the safety as well as the potential clinical efficacy of an adoptive transfer of CD8+ T cells, sorted with HLA-peptide multimers and specific for Melan-A and MELOE-1 melanoma antigens, to patients suffering from advanced metastatic melanoma (stages IIIc and IV).

Timeline

Start
2015-05-26
Primary completion
2019-05-06
Completion
2019-05-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Melanoma antigens-specific CD8+ T lymphocytes Cell therapy — Intravenous

Indications