drugset / Trial / NCT02433977

The Effects of NOx and Conjugated Linoleic Acid on Asthmatics

NCT02433977

Phase 2 Completed 6 enrolled Gladwin, Mark, MD
NaSingle-groupOpen-labelTreatment

Summary

This study will examine the hypothesis that in obese asthmatics; treatment with NOx + CLA is well tolerated, safe and will increase eNO while reducing airway oxidative stress. Allied with this, the investigators will define whether supplementing with this bioactive mediator modifies the airway microbiome, and reduces airway inflammation.

Timeline

Start
2015-09
Primary completion
2019-11
Completion
2019-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Conjugated Linolenic Acid Unknown 3 g Oral
Subject Sodium Nitrate Other / unclassified 1 g Oral
Subject Sodium Nitrite Small molecule 20 mg Oral

Indications