drugset / Trial / NCT02437708

Regenerative Endodontic Procedure of Immature Permanent Teeth With L-PRF: a Pilot Controlled, Clinical Trial

NCT02437708

Phase 3 Completed 29 enrolled Universitaire Ziekenhuizen KU Leuven
Non-randomizedParallel-groupSingle-blindTreatment

Summary

This study evaluates the impact of autologous 'leucocyte and platelet rich fibrin' (L-PRF) on the periapical bone healing and further root development of infected immature permanent teeth. In the test group regenerative endodontic procedure (REP) is performed with L-PRF as scaffold, in the control group REP without L-PRF is performed .

Timeline

Start
2014-09
Primary completion
2019-08
Completion
2020-10

Publications

  • Background Diogenes A, Michael AH, Teixeira FB, Hargreaves KM. An update on clinical regenerative endodontics. Endod Top. 2013;28:2-23.

Drugs

EvaluationDrugModalityDoseRoute
Subject rHIV7-shI-TAR-CCR5RZ-transduced Hematopoietic Stem/Progenitor Cells Unknown Other

Indications

No indication recorded.