drugset / Trial / NCT02439944

Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement

NCT02439944

Phase 2/3 Terminated 18 enrolled Centre for Addiction and Mental Health
RandomizedParallel-groupOpen-labelTreatment

Summary

This study involves the use of personalized nicotine patch dosing as a treatment strategy for smokers who cannot quit smoking after 2 weeks of using the standard nicotine patch dose. Functional Magnetic Resonance Imaging scans will also be obtained from all study participants before and after treatment. The first aim of the study is to determine if the treatment method under investigation is safe and more effective at increasing quit rates in smokers who do not respond to standard therapy.The second aim is to determine if there are any treatment- or cessation-related changes in brain function.

Timeline

Start
2015-07
Primary completion
2017-12
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Nicotine Unknown 21 mg Other
Comparator Nicotine Unknown Other

Indications