drugset / Trial / NCT02442648

B-Cell Targeted Carfilzomib Desensitization

NCT02442648

Phase 1 Unknown 32 enrolled E. Steve Woodle Amgen · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

The primary purpose of this study is to provide a preliminary evaluation of the safety and potential efficacy of carfilzomib in reducing HLA antibody levels in highly sensitized kidney transplant candidates.

Timeline

Start
2014-12
Primary completion
2021-06
Completion
2021-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Carfilzomib Other / unclassified
Subject Rituximab Monoclonal antibody

Indications

No indication recorded.