Comparison of Immunization Schedules of Inactivated Hepatitis A Vaccine and Combined Hepatitis A and Hepatitis B Vaccine

Phase 4 Completed 301 enrolled Sinovac Biotech Co., Ltd

RandomizedParallel-groupDouble-blindPrevention

Summary

The purpose of this study is to compare the immunogenicity and safety of three different immunization schedules of inactivated hepatitis A vaccine (HAV) and/ or combined hepatitis A and B vaccine (HABV) in healthy Chinese infants.

Timeline

Start: 2014-05
Primary completion: 2015-01
Completion: 2016-06

Publications

Li F, Hu Y, Zhou Y, Chen L, Xia W, Song Y, Tan Z, Gao L, Yang Z, Zeng G, Han X, Li J, Li J. A Randomized Controlled Trial to Evaluate a Potential Hepatitis B Booster Vaccination Strategy Using Combined Hepatitis A and B Vaccine. Pediatr Infect Dis J. 2017 May;36(5):e157-e161. doi: 10.1097/INF.0000000000001535.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Hepatitis B vaccine	Vaccine	5 ug	Intramuscular
Subject	Hepatitis B vaccine	Vaccine	0.5 ml	Intramuscular
Subject	Hepatitis B vaccine	Vaccine	250 iu	Intramuscular
Subject	Inactivated hepatitis A vaccine	Vaccine	0.5 ml	Intramuscular
Subject	Inactivated hepatitis A vaccine	Vaccine	250 iu	Intramuscular

Comparison of Immunization Schedules of Inactivated Hepatitis A Vaccine and Combined Hepatitis A and Hepatitis B Vaccine

Summary

Timeline

Publications

Drugs

Indications