drugset / Trial / NCT02446002
Assessment of the Effect of Naltrexone on Lofexidine Single Dose Pharmacokinetics in Healthy Subjects
Phase 1
Completed
25 enrolled
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA) · collab
NaSingle-groupOpen-labelTreatment
Summary
A Phase 1, open-label, single-arm study with two single doses of lofexidine and multiple doses of naltrexone in healthy adult subjects to determine the effect of naltrexone on the single dose pharmacokinetics of the oral lofexidine formulation.
Timeline
- Start
- 2015-05
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lofexidine | Small molecule | 0.4 mg | Oral |
| Subject | Naltrexone | Small molecule | 50 mg | Oral |
Indications
No indication recorded.