drugset / Trial / NCT02447224
Pilot Trial of Antibiotics Versus Surgery for Treating Acute Appendicitis
Phase 0
Completed
30 enrolled
Olive View-UCLA Education & Research Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The major goal of the project is to demonstrate the feasibility of conducting a multi-center randomized clinical trial of antibiotic therapy versus appendectomy for the treatment of patients with acute uncomplicated appendicitis by conducting a single-site pilot study so as to optimize the chance of a large multi-center clinical trial's future success.
Timeline
- Start
- 2015-03
- Primary completion
- 2015-10
- Completion
- 2017-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ertapenem | Small molecule | 1 g | Intravenous |
| Subject | Metronidazole | Small molecule | — | Oral |
| Subject | cefdinir | Other / unclassified | — | Oral |