drugset / Trial / NCT02447315

A Study to Investigate the Effect of Oral Doses of Pilocarpine on Salivary Secretion and Static Pupillometry in Healthy Subjects

NCT02447315

Phase 1 Completed 12 enrolled Astellas Pharma Europe B.V.
RandomizedCrossoverDouble-blindBasic science

Summary

The purpose of this study is to evaluate the pharmacodynamic effect of oral doses of pilocarpine on salivary secretion in healthy male and female subjects. In addition, pharmacodynamic effect on static pupillometry will be evaluated as well as pharmacokinetics and safety and tolerability of oral doses of pilocarpine in healthy subjects.

Timeline

Start
2015-05
Primary completion
2015-06
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Pilocarpine Unknown Oral

Indications

No indication recorded.