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drugset / Trial / NCT02447640

PET Imaging Study to Evaluate the mGlu5r Occupancy Following ADX48621 (Dipraglurant) Administration

NCT02447640 ↗

Phase 1 Completed 12 enrolled Johns Hopkins University Addex Pharma S.A. · collab
Non-randomizedSingle-groupOpen-labelOther

Summary

This is an open label study, non-randomized, positron emission tomography (PET)study investigating mGlu5 receptor occupancy after single or two oral dosing of ADX48621 in healthy subjects using \[18F\]-FPEB as the radiotracer.

Timeline

Start
2015-04
Primary completion
2017-12
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Dipraglurant Small molecule 100 mg Oral
Subject Dipraglurant Small molecule 200 mg Oral
Subject Dipraglurant Small molecule 400 mg Oral

Indications

No indication recorded.