drugset / Trial / NCT02453581
Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers
Phase 1
Completed
24 enrolled
Medicines for Malaria Venture
Queensland Institute of Medical Research · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
A single centre, open, controlled study using Blood Stage Plasmodium falciparum challenge inoculum (BSPC) as a model to assess the effectiveness of three dose levels of the experimental anti-malarial product, OZ439.
Timeline
- Start
- 2012-09
- Primary completion
- 2013-03
- Completion
- 2013-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Artefenomel | Small molecule | 100 mg | Oral |
| Subject | Artefenomel | Small molecule | 200 mg | Oral |
| Subject | Artefenomel | Small molecule | 500 mg | Oral |