drugset / Trial / NCT02454842

Study for Treatment With TH-4000 (Tarloxotinib) in Epidermal Growth Factor Receptor (EGFR) Mutant, T790M-negative Non-small Cell Lung Cancer (NSCLC) Patients

NCT02454842 ↗

Phase 2 Terminated 21 enrolled Rain Oncology Inc
NaSingle-groupOpen-labelTreatment

Summary

This phase 2 study is designed to evaluate the safety and activity of TH-4000 a hypoxia-activated prodrug, in patients with EGFR-Mutant, T790M-Negative, Advanced NSCLC.

Timeline

Start
2015-06
Primary completion
2017-01
Completion
2017-01-31

Outcome

Outcome not reported

Stopped: “Lack of efficacy”

Drugs

EvaluationDrugModalityDoseRoute
Subject TH-4000 Other / unclassified 150 mg/m2 Intravenous