drugset / Trial / NCT02455479
Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals
Phase 1
Recruiting
150 enrolled
Weill Medical College of Cornell University
National Institute on Drug Abuse (NIDA) · collab
RandomizedSequentialTriple-blindTreatment
Summary
The purpose of this study is to assess the safety and preliminary efficacy of an anti-cocaine vaccine called dAd5GNE in cocaine-dependent individuals. It uses the concept of a vaccine to treat the neurological effects of cocaine by evoking "immunity" to prevent the effects of cocaine on the brain.
Timeline
- Start
- 2012-06-26
- Primary completion
- 2026-12
- Completion
- 2027-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | dAd5GNE | Vaccine | 100 ug | — |
| Subject | dAd5GNE | Vaccine | 316 ug | — |
| Subject | dAd5GNE | Vaccine | 1000 ug | — |