Reversal of Dabigatran With Prothrombin Complex Concentrate

Summary

The purpose of this study is to investigate whether Prothrombin Complex Concentrate (PCC) is effective in reversing the anticoagulant effect of Dabigatran, as assessed by two modified skin-bleeding tests.

Timeline

Start

2015-01

Primary completion

2016-07

Completion

2016-12

Publications

• Background Wolzt M, Eder M, Weltermann A, Entlicher J, Eichler HG, Kyrle PA. Comparison of the effects of different low molecular weight heparins on the hemostatic system activation in vivo in man. Thromb Haemost. 1997 Aug;78(2):876-9.

Drugs

Indications

No indication recorded.