drugset / Trial / NCT02470832
A Study to Investigate the Effect of CYP3A Inhibition on the Pharmacokinetics of RG1662 in Healthy Subjects
Non-randomizedCrossoverOpen-labelTreatment
Summary
The study is being conducted to investigate the effect of itraconazole treatment in the pharmacokinetics of RG1662. It is also to evaluate the exposure of RG1662 vs. QTc response relationship and the safety and tolerability of RG1662 when given in combination with itraconazole in healthy subjects.
Timeline
- Start
- 2015-05
- Primary completion
- 2015-07
- Completion
- 2015-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Basmisanil | Small molecule | 120 mg | Oral |
| Subject | Itraconazole | Small molecule | 200 mg | — |
Indications
No indication recorded.