Spinal Anaesthesia With Chloroprocaine HCl 1% for Elective Lower Limb Procedures of Short Duration.

Phase 2 Completed 45 enrolled Sintetica SA Cross S.A. · collab

RandomizedParallel-groupSingle-blindOther

Summary

This study evaluate the effect of 3 doses of Chloroprocaine HCl 1% (30, 40 and 50 mg) for spinal anaesthesia in adult patients undergoing short duration elective surgery of the lower limb. Patients undergoing elective short-duration lower limb surgery will be randomised into 3 treatment groups (15 patients per group) to receive one of the 3 single doses of Chloroprocaine HCl 1%, i.e. either D1, D2 or D3, via intrathecal injection.

Timeline

Start: 2015-06
Primary completion: 2015-11
Completion: 2015-11

Publications

Ghisi D, Boschetto G, Spinelli AM, Giannone S, Frugiuele J, Ciccarello M, Bonarelli S. Spinal anaesthesia with Chloroprocaine HCl 1% for elective lower limb procedures of short duration: a prospective, randomised, observer-blind study in adult patients. BMC Anesthesiol. 2021 Feb 20;21(1):58. doi: 10.1186/s12871-021-01279-9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chloroprocaine HCl 1%	Unknown	30 mg	Intrathecal
Subject	Chloroprocaine HCl 1%	Unknown	40 mg	Intrathecal
Subject	Chloroprocaine HCl 1%	Unknown	50 mg	Intrathecal

Indications

No indication recorded.