A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease

Summary

The purpose of this study is to determine whether ticagrelor is effective in reducing the number of days of pain, intensity of pain, and reducing the use of analgesics due to sickle cell disease

Timeline

Start

2015-07-09

Primary completion

2016-11-16

Completion

2016-11-16

Outcome

Missed primary endpoint

registry Mean Difference (Final Values) 0.0450 (90% CI -0.0610 to 0.1510); Mixed Models Analysis NCT02482298 ↗

registry Mean Difference (Final Values) 0.0801 (90% CI -0.0230 to 0.1832); Mixed Models Analysis NCT02482298 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ticagrelor	Small molecule	10 mg	Oral
Subject	Ticagrelor	Small molecule	45 mg	Oral

Indications