The Effect of Sumatriptan and Placebo on Isosorbide-5-mononitrate Induced Headache

Summary

To develop a pragmatic migraine model the investigators will induce headache in healthy volunteers and in patients with migraine without aura with a long lasting Nitrogen Oxide (NO) donor. If the headache responds to sumatriptan, the model can be used to test new drug candidates.

Timeline

Start

2015-04

Primary completion

2015-08

Completion

2015-08

Drugs

Indications