drugset / Trial / NCT02485548
Cisplatin Plus Raltitrexed or 5-fluorouracil Concurrent With Radiotherapy for Head and Neck Squamous Cell Cancer
Phase 3
Unknown
120 enrolled
Jiangsu Cancer Institute & Hospital
Affiliated Hospital of Jiangnan University · collabChangzhou Cancer Hospital of Soochow University · collabNanjing BenQ Hospital · collabNorthern Jiangsu People's Hospital · collabThe First Affiliated Hospital with Nanjing Medical University · collabThe Second Hospital of Nanjing Medical University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a multicenter phase Ⅲ trial. The objective is to compare the efficacy and toxicity of cisplatin plus raltitrexed or 5-fluorouracil in concurrence with IMRT for patients with locoregionally advanced head and neck squamous cell cancer.
Timeline
- Start
- 2015-06
- Primary completion
- 2018-06
- Completion
- 2018-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Raltitrexed | Small molecule | — | — |
| Comparator | fluorouracil | Small molecule | — | — |
| Background | Cisplatin | Other / unclassified | — | — |