drugset / Trial / NCT02491697

Immunotherapy Combined With Capecitabine Versus Capecitabine Monotherapy in Advanced Breast Cancer

NCT02491697

Phase 2 Active not recruiting 400 enrolled The First People's Hospital of Changzhou
RandomizedParallel-groupOpen-labelTreatment

Summary

The prognosis of advanced breast cancer does not improve much recently although varies of adjuvant drugs have been tried.Dendritic cells co-cultured with cytokine-induced killer cells(DC-CIK) immunotherapy has been proved to improve survival in several cancers, but its role in advanced breast cancer stains unclear. The purpose of this study is to evaluate the efficacy and safety of DC-CIK immunotherapy combined with capecitabine versus capecitabine monotherapy for the treatment of advanced breast cancer.

Timeline

Start
2016-02
Primary completion
2030-08
Completion
2033-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 2500 mg/m2
Subject DC-CIK Cell therapy

Indications