A Study of the Absorption, Metabolism, and Excretion of GBT440 in Healthy Male Subjects

Summary

This study will provide information regarding the metabolic pathway of GBT440, the need for evaluation of potential drug-drug interactions, and the need for studies in special populations. The administration of radiolabeled drug is necessary to fully characterize the rates and routes of elimination of GBT440, providing further quantitative information on the disposition of GBT440. The results from this study will permit a comprehensive comparison between animal and human routes of elimination and metabolic profiles of GBT440.

Timeline

Start

2015-06

Primary completion

2016-07

Completion

2016-07

Drugs

Indications